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    When calculating the sample size is not necessary

    Thank you so much. Best regards
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    When calculating the sample size is not necessary

    Thank you so much for your answer. It is a retrospective study (observing past information) and we need to determine the % of the persistence of a drug use at a one-year since the first dispensation. I already determine the sample size, but I was asked if it is really necessary, considering the...
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    When calculating the sample size is not necessary

    Hi everyone. I am planning to do an observational study in which it is intended to analyze the dispensation in pharmacies of a certain drug. I will have access to the entire dispensing database for this drug, is it necessary to determine the sample size? If calculation is not necessary, how...
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    Sample size determination

    Hello everyone. I would like to ask your help on the decision about the best methodology to determine the sample size to conduct an observational study. This is a study to be carried out by a pharmaceutical company in which it is intended to characterize all combinations of drugs used before...