A biomedical experiment problem

yuppy

New Member
#1
Dear people,

I am currently doing a biomedical study where there are 4 different treatment. Sham operation, A, B and (A+B). Each treatment have the same 4 time points. (0, 15, 30 & 45) The sample size for each group is 5.

I am doing a proteomics study... i.e each group will give 400+ different proteins which I have to compare them by intensity (Done by computer). However, I need to compare each protein by the treatment (A+B) to the rest with respective to time.

I am sorry, my statistical knowledge is limited to 1 way annova and student t test. Will try SPSS but not very good.

Any suggest how do I tackle this problem?

Thank you!
 

JohnM

TS Contributor
#2
You may need to do a repeated-measures ANOVA, since each treatment is measured at 4 successive times, and within each treatment, the time measurements will be related.
 

yuppy

New Member
#3
Thanks for the quick reply.

However from my understand of repeated-measures ANOVA, the same samples are taken several times. However within my treatment I have already have a sample size of n=5 in each time point.

Is already a repeated-measures ANOVA? Should I just do repeated-measures ANOVA the whole thing or can I do ANOVA of the regression with respect to time of the treatment?
 
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