I am currently doing a biomedical study where there are 4 different treatment. Sham operation, A, B and (A+B). Each treatment have the same 4 time points. (0, 15, 30 & 45) The sample size for each group is 5.

I am doing a proteomics study... i.e each group will give 400+ different proteins which I have to compare them by intensity (Done by computer). However, I need to compare each protein by the treatment (A+B) to the rest with respective to time.

I am sorry, my statistical knowledge is limited to 1 way annova and student t test. Will try SPSS but not very good.

Any suggest how do I tackle this problem?

Thank you!