Hey,
I had someone ask me if I could create a dose response curve for them. They have a dose amount and associated response which is a time to event. I believe everyone will have an event, so I have a continuous response value to work with (but I have a feeling there will only be 2-3 dose amounts - e.g., 1.2, 1.4, 1.6). I have not seen these data yet. Last part is they have subgroupings, say males/females and also other drugs with comparable data (dose, time).
I have not met with the person, but I wouldn't be surprised if they want me to calculate dose response curves for subgroups or compare response curves between groups. A quick look showed these data are usually analyzed with log logistic model. I was going to see if anyone had some insights or references. I can post example data when I get them, but I imagine it will be like the following with few dose amounts and with multiple units per dose amount. Also each unit is unique, these aren't repeat measures.
does response
1.2 123
1.2 134
1.4 100
1.4 90
@Miner
@rogojel
@GretaGarbo
Do you all have any experience with such data?
I had someone ask me if I could create a dose response curve for them. They have a dose amount and associated response which is a time to event. I believe everyone will have an event, so I have a continuous response value to work with (but I have a feeling there will only be 2-3 dose amounts - e.g., 1.2, 1.4, 1.6). I have not seen these data yet. Last part is they have subgroupings, say males/females and also other drugs with comparable data (dose, time).
I have not met with the person, but I wouldn't be surprised if they want me to calculate dose response curves for subgroups or compare response curves between groups. A quick look showed these data are usually analyzed with log logistic model. I was going to see if anyone had some insights or references. I can post example data when I get them, but I imagine it will be like the following with few dose amounts and with multiple units per dose amount. Also each unit is unique, these aren't repeat measures.
does response
1.2 123
1.2 134
1.4 100
1.4 90
@Miner
@rogojel
@GretaGarbo
Do you all have any experience with such data?