Help! Looking for appropriate analysis for 2 points data set

#1
Title is pretty forward... I know I could use an ANOVA in theory, since I am looking at the change of my DV caused by an IV.

The only thing that makes me unsure of what is the appropriate analysis is that I actually want to see if the change in my IV affects the change in my DV.

For example: I want to see if the change in employment (being employed at baseline and unemployed at 5 years follow-up) will affect depression level (not depressed at baseline and depressed at 5 years follow-up). Does regulare 'repeated measures ANOVA' capture that effect& I'm a bit rusty, so I need guidance!! :)