How to find the statistical significance between percentages in two different samples

#1
Hi,
we are analyzing healthcare data between pre (2017 data) and post (2018 data) implementation of Dosage recommendations. The study groups are different. So, we want to see a statistical difference between the population. For example, 2017 has 56% female population and 2018 has 43% female population. We want to see the statistical difference between these two percentages. Which test is the appropriate one? Thank you so much in advance.