Hi,
I am a bit of a novice of this so for give my ignorance.
Essentially i have two groups of data. One is for people with exon 19 mutations the other for those with exon 21 mutations.
Each group has different sample sizes with variables including overall survival etx. The overall survival data is a continuous variable.
My boss has asked my to calculate the means with confidence intervals of each group which I have been able to do.
She also wants p values to compare the OS between the 2 groups which has been a lot more difficult for me to calculate.
the first issue is the data is not normally distributed so i cant use ttest. I tried transforming but that did not work.
The next suggestion was to try to do a nonparametric test  Wilcoxan rank sum.
hoever the problem is I don't have a grouping variable; so i can't proceed with the test. I suppose the grouping would be the outcome would be Overall survival in exon 19 or exon 21 but this is not a separate variable in my data so i can't input it...
i'll attach an image of my problem
sorry for making any simple mistakes. thanks
I am a bit of a novice of this so for give my ignorance.
Essentially i have two groups of data. One is for people with exon 19 mutations the other for those with exon 21 mutations.
Each group has different sample sizes with variables including overall survival etx. The overall survival data is a continuous variable.
My boss has asked my to calculate the means with confidence intervals of each group which I have been able to do.
She also wants p values to compare the OS between the 2 groups which has been a lot more difficult for me to calculate.
the first issue is the data is not normally distributed so i cant use ttest. I tried transforming but that did not work.
The next suggestion was to try to do a nonparametric test  Wilcoxan rank sum.
hoever the problem is I don't have a grouping variable; so i can't proceed with the test. I suppose the grouping would be the outcome would be Overall survival in exon 19 or exon 21 but this is not a separate variable in my data so i can't input it...
i'll attach an image of my problem
sorry for making any simple mistakes. thanks
Attachments

135.7 KB Views: 5

133.9 KB Views: 5