Reproducibility/replicate using F test or paired T-Test?

#1
Hi, can i know for the reproducibility or in other words replicate to decide on the test is it pass or fail, using F test or Paired T-test? I'm having lab here. We are doing the test here as quality assurance in our lab. We are facing problem to decide is it pass or fail.

Im trying to used both test but from my reading, research, supposedly using paired T-Test because from my understanding, this test is not independent test.

I hope i can get some help or opinion from other experts on this.

Thanks.