This is how I read the situation. RedNightSkies RNS has three groups - perhaps C a control non treatment group, P a placebo group and T a treatment group. There is a variable x which may or may not influence a response y. RNS has a shrewd idea that in group T the effect of x will be seen and the graph of y vs x will show a rise (or fall) while the graphs of C and P will be more of less flat. RNS draws the graphs and it looks plausible. No doubt these three graphs will appear in the final paper. All RNS needs now are some p values to confirm it all.
A simple (some might say simplistic) approach is to do the three regressions and see if graph T has a significant slope and C and P do not. A careful researcher may check that the residuals in each graph are normal and even (but not necessarily the same variance), and a cautious researcher will likely adjust the critical significance cutoff to allow for multiple p's.
A more hard core analyst might put all the data into one linear model with Group, x and the interaction Group*x or some similar variation. The idea is that hopefully the interaction will be significant indicating that at least one slope is different from the others. (The advantage of this combined LM is that error df is higher, meaning that the critical F values are slightly smaller and so the power is increased, but only extremely slightly with samples of this size.) A careful analyst would check the residuals and ensure that they were normal within each group and additionally they had equal variance across the groups. This is more stringent and more work than the simple approach.
Fortunately, the interaction turns out to be significant. However, this shows only that there are differences between the slopes, not that T is significant and C and P are not. This can no doubt be shown by considering the size and SE of the various estimates but it is hard work and not obvious. In any event, this will involve three comparisons and so a cautious analyst will adjust the critical significance cutoff to allow for multiple p's.
In short, I would suggest that the best approach is the three regressions. As I said before, it is easy to do, easy to interpret and easy to explain.