Hi there,
I'm comparing image values in a tumour region before and after treatment. I'm trying to see if the value of the pixels is significantly different after treatment. The histogram distributions look like this (for one tumour):
I assumed using the 'two-sample test assuming unequal variances' option in excel would be appropriate here, but it seems overly sensitive - as in, it's saying pretty much almost all of them are statistically significant differences (except for a few). This would be fine, except that it says this is p<0.000001:
And to me, that just.... seems wrong? As in, those two distributions are almost identical.. it seems dishonest to call that change statistically significant.
Please help, should I be using something else? Or changing what alpha threshold I consider significant?
I'm comparing image values in a tumour region before and after treatment. I'm trying to see if the value of the pixels is significantly different after treatment. The histogram distributions look like this (for one tumour):

I assumed using the 'two-sample test assuming unequal variances' option in excel would be appropriate here, but it seems overly sensitive - as in, it's saying pretty much almost all of them are statistically significant differences (except for a few). This would be fine, except that it says this is p<0.000001:

And to me, that just.... seems wrong? As in, those two distributions are almost identical.. it seems dishonest to call that change statistically significant.
Please help, should I be using something else? Or changing what alpha threshold I consider significant?