fdr

Hi everyone, I am running some omics experiments where I compare a treated and an untreated condition. In order to compare them, I am computing a t-test and my output are fold changes and p-values. In this dataset, I only have very vew changes (this is to be expected for this dataset) but I...

Dear all, I would like to request your help and opinions on a meta-analysis setup utilizing two completely independent cancer cohorts, where one acts as discovery data set, while the other is meant as validation cohort. To 'integrate' both cohorts, I would like to select genes by FDR in...

I am looking for a procedure/code to control FDR in a multiple regression analysis, including 1 DV and 28 IVs (some of them interaction terms). Some IVs are correlated. Where can I find the appropriate FDR procedure/code for this problem? Thanks. Salar

Hi, I'm using Affymetrix microarrays to check if there exist some differences in the gene expression of two group of animals that have been differently treated. I'm using a t-test with permutations (as my groups only have three animals and I read that it is better to use permutation if you...