proteomics

Hi folks, I am working with proteomics data, containing mainly LC-MS and NMRI analysis. Firstly, I must normalise data to give valuable compound for biostatistics analysis such as data imputation. I have never had to deal with such data. Can you advise me on which method to choose (I usually...

Dear All, I am new here and this is my first post. I have a problem where I am comparing a set of 9 protein amino acid (AA) sequences (Proteins I am interested in) vs 1000 random of proteins sequence sets 9 by 9. Basically, I am trying to confirm that some AA (e.g. Alanine) are enriched in my...

Hello all, I'm working with quantification of some modified peptides enriched from serum of sick and healthy people. In the crude data (integrated LC-MS peak areas) this modification appears to be significantly more abundant in sick people's serum, which is the hypothesis, and also consistent...