Automated multivariate nonlinear regression

#1
I have 4,300 lines of data that looks like this in each column:
Code:
IV1, IV2, IV3, DV1, DV2
It has five columns, three are IVs, two are DVs. How can I perform multivariate nonlinear regression on all 4300 lines of data to see how the IVs affect each DV automatically with a program?