Hello everyone,
I am studying immue cell distribution in different types of nontomourous (n=66), precancerous (n=67) and malignant tissues (n=48) in a single patient cohort. As you can see in the violin plot attached below, I started out by applying the KW test to compare the distribution in the 3 groups (normal versus precancerous vs invasive) [p value seen on graph] and now I want to do a pairwise comparisions to find out where the difference actually relies.
if I tried both Dunn's post hoc test and mutliple MannWhitneyU tests between the groups, and obviously ended up with different significant results... The results on the graph are those of the pairwise MWU tests...
Is it appropriate to apply multiple MWU tests after KW in this particular setting? I obviously "planned" to compare the 3 different groups all along, so my pvalues weren't really meant to be post hoc...
My supervisor says it's fine to use multiple MWU tests in this case, but I want to have other opinions.
Thank you very much for you help! (and yes, I'm definitely a stat newbie)
I am studying immue cell distribution in different types of nontomourous (n=66), precancerous (n=67) and malignant tissues (n=48) in a single patient cohort. As you can see in the violin plot attached below, I started out by applying the KW test to compare the distribution in the 3 groups (normal versus precancerous vs invasive) [p value seen on graph] and now I want to do a pairwise comparisions to find out where the difference actually relies.
if I tried both Dunn's post hoc test and mutliple MannWhitneyU tests between the groups, and obviously ended up with different significant results... The results on the graph are those of the pairwise MWU tests...
Is it appropriate to apply multiple MWU tests after KW in this particular setting? I obviously "planned" to compare the 3 different groups all along, so my pvalues weren't really meant to be post hoc...
My supervisor says it's fine to use multiple MWU tests in this case, but I want to have other opinions.
Thank you very much for you help! (and yes, I'm definitely a stat newbie)
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