Hi everyone,
I was looking for some suggestions on ho to compute sample size for a non-inferiority trial. The problem is that I do not have studies with previous effect sizes of the active comparator to use for establishing a non-inferiority margin. What would you suggest to do in this case?
Thanks in advance
I was looking for some suggestions on ho to compute sample size for a non-inferiority trial. The problem is that I do not have studies with previous effect sizes of the active comparator to use for establishing a non-inferiority margin. What would you suggest to do in this case?
Thanks in advance